Biggest races where rider never competed
Major races where Caoimhe O'Brien never competed in.
| # | Race | Class |
|---|---|---|
| 1 | La Flèche Wallonne Féminine | 1.WWT |
| 2 | Giro d'Italia Internazionale Femminile | 2.WWT |
| 3 | Trofeo Alfredo Binda - Comune di Cittiglio | 1.WWT |
| 4 | Boels Ladies Tour | 2.WWT |
| 5 | World Championships WE - ITT | WC |
| 6 | Women's WorldTour Ronde van Drenthe | 1.WWT |
| 7 | Premondiale Giro Toscana Int. Femminile - Memorial Michela Fanini | 2.2 |
| 8 | Postnord UCI WWT Vårgårda WestSweden RR | 1.WWT |
| 9 | Omloop Het Nieuwsblad WE | 1.1 |
| 10 | Internationale Lotto Thüringen Ladies Tour | 2.1 |
| 11 | WWT Emakumeen Bira | 2.WWT |
| 12 | Durango-Durango Emakumeen Saria | 1.2 |
| 13 | Drentse Acht van Westerveld | 1.2 |
| 14 | Postnord UCI WWT Vårgårda WestSweden TTT | 1.WWT |
| 15 | Gent-Wevelgem In Flanders Fields WE | 1.WWT |
| 16 | Festival Elsy Jacobs | 2.1 |
| 17 | Strade Bianche Donne | 1.WWT |
| 18 | Olympic Games WE - Road Race | Olympics |
| 19 | La Course by Le Tour de France | 1.WWT |
| 20 | Milano-Sanremo Donne | 1.WWT |
| 21 | Healthy Ageing Tour | 2.1 |
| 22 | Gracia - Orlová | 2.2 |
| 23 | Liège-Bastogne-Liège Femmes | 1.WWT |
| 24 | Grand Prix de Dottignies | 1.2 |
| 25 | Tour Cycliste Féminin International de l'Ardèche | 2.1 |